약학대학 - 약학대학

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학술지 논문

  • (2019)  Emerging PEGylated non-biologic drugs.  EXPERT OPINION ON EMERGING DRUGS.  24,  2
  • (2019)  Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma.  NATURE COMMUNICATIONS.  10,  1
  • (2018)  Chemical chaperone-conjugated exendin-4 as a cytoprotective agent for pancreatic β-cells.  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY.  105,  1
  • (2018)  Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.  NATURE MEDICINE.  24,  7
  • (2017)  PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells.  JOURNAL OF CONTROLLED RELEASE.  267,  Special SI
  • (2017)  Cancer preventive effect of recombinant TRAIL by ablation of oncogenic inflammation in colitis-associated cancer rather than anticancer effect..  ONCOTARGET.  9,  2
  • (2017)  Reducing agent-free synthesis of curcumin-loaded albumin nanoparticles by self-assembly at room temperature.  INTERNATIONAL JOURNAL OF PHARMACEUTICS.  529,  1-2
  • (2017)  Brushing off antigenicity.  NATURE BIOMEDICAL ENGINEERING.  1,  1
  • (2017)  Brushing off antigenicity.  Nature Biomedical Engineering.  1,  1
  • (2017)  The synthesis of tamoxifen-loaded albumin nanoparticles by homogenizers: Optimization and in vitro characterization.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.  41,  1
  • (2016)  Exendins and exendin analogs for diabetic therapy: a patent review (2012-2015).  EXPERT OPINION ON THERAPEUTIC PATENTS.  26,  7
  • (2016)  Trimeric PEG-Conjugated Exendin-4 for the Treatment of Sepsis.  BIOMACROMOLECULES.  17,  3
  • (2015)  Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors.  JOURNAL OF CONTROLLED RELEASE.  220,  1
  • (2015)  Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells..  HEPATOLOGY.  63,  1
  • (2015)  What is the future of PEGylated therapies?.  EXPERT OPINION ON EMERGING DRUGS.  20,  4
  • (2015)  Mono-lithocholated exendin-4-loaded glycol chitosan nanoparticles with prolonged antidiabetic effects.  INTERNATIONAL JOURNAL OF PHARMACEUTICS.  495,  1
  • (2015)  Doxorubicin-Bound Albumin Nanoparticles Containing a TRAIL Protein for Targeted Treatment of Colon Cancer.  PHARMACEUTICAL RESEARCH.  33,  3
  • (2015)  In situ facile-forming PEG cross-linked albumin hydrogels loaded with an apoptotic TRAIL protein.  JOURNAL OF CONTROLLED RELEASE.  214,  1
  • (2015)  Differences in electrophoretic behavior between linear and branched PEG-conjugated proteins.  ELECTROPHORESIS.  36,  1
  • (2015)  Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.  ACTA BIOMATERIALIA.  12,  1

단행본

  • (2009)  Delivery Techonologies for Biopharmaceuticals Chapter 12: Advanced pulmonary delivery of peptides or proteins using polymeric particles.  WILEY.  공동
  • (2003)  대한약전 8개정 해설서.  신일상사.  공동
  • (1998)  대한 약전 7개정 해설서.  공동

특허/프로그램

  • 엑센딘의 비강투여용 악제학적 조성물 및 이의 제조방법.  2009-0064852.  20120130.  대한민국
  • 폴리에틸렌글리콜로 화학적으로 수식된 인간 성장 호르몬, 이의 제조방법 및 용도.  2009-0042035 .  20120103.  대한민국
  • 암 표적지향형 트랜스페린 - 폴리에틸렌 글리콜이 수식된 트레일, 이의 제조 및 용도.  2009-0088126.  20111212.  대한민국
  • N - 말단이 수식된 PEG - TRAIL 결합체, 이의 제조 방법 및 이의 용도.  10-2007-0038655.  20090925.  대한민국
  • 가지 달린 고분자 유도체와 인터페론 결합체를 포함하는 항바이러스제.  10-2002-0002651.  20090305.  대한민국
  • 항고지혈, 항산화 및 항바이러스 활성을 갖는 참취 추출물 및 그로부터 분리된 화합물.  10-2000-037983-0.  20090130.  대한민국
  • 비오틴으로 수식된 엑센딘 유도체, 이의 제조방법 및 이의용도.  10-0864584-0000.  20081014.  대한민국
  • 비오틴과 비오틴-폴리에틸렌글리콜이 접합된 GLP-1유도체, 이의 제조방법 및 이를 포함하는 약학 조성물.  0778633.  20071115.  대한민국
  • 단백질 또는 펩타이드에 결합되는 다가지의 고분자 유도체와 접합체.  10-0761652-00-00.  20070918.  대한민국
  • 소수성 담즙산이 접합된 엑센딘-4 유도체, 이의 제조방법및 이를 포함하는 약학 조성물.  10-0746658.  20070731.  대한민국
  • 새로운 이부프로펜 함유 잴라틴 초미세 미립구.  10-0694235-00-00.  20070306.  대한민국
  • 고반응성의 가지 달린 고분자 유도체 및 고분자와 단백질 또는 펩타이드의 접합체.  0396983.  20030816.  대한민국
  • The nasal transmucosal delivery of peptides conjugated with biocompatible polymers.  US6,506,730B1.  20030114.  미국
  • 생체적합성고분자가 수식된 펩타이드의 비점막 전달.  0345214.  20020705.  대한민국

학술회의논문

  • (2016)  Strategic PEGylation: Half-life extension of biologic drugs.  8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems.  스페인
  • (2015)  Smart PEGylation: Enabling Extended Half-life without Loss of Bioactivity..  2014 CRS Annual Meeting.  미국
  • (2015)  PEGylation and Bioconjugation of Peptide and Protein Drugs and there Drug Delivery Systems.  1st International Pharmacy Materials 2015 Symposium.  인도네시아
  • (2014)  Noble Long-Acting GLP-1 Receptor agonist Analogue.  BIT’S 3RD ANNUAL WORLD CONGRESS OF DIABETES 2014.  중국
  • (2014)  Strategic Approach for the PEGylation of GLP-1 Analogues.  17th International Pharmaceutical Technology Symposium.  튀르키예
  • (2011)  PEGylated Peptide and Protein Drugs.  2011년 대한약학회 추계학술대회 초록집.  대한민국
  • (2011)  Preparation and Characterization of Inhalable Self-assembled Glycol Chitosan Nanogels Containing Palmitylated Exendin-4.  추계 약학회 초록.  대한민국
  • (2011)  Praparation and Characterization of a Long-acting Anti-diabetic inhalation System of Self-assembled Chitosan Nanogel Containing Fatty-acylated Exendin-4 Peptide.  2011 AAPS 초록.  미국
  • (2011)  Preparation and Evaluation of Doxorubicin-loaded Albumin Nanoparticles Surface-conjugated with TNF-related Apoptosis Inducing Ligand (TRAIL) and Transferrin for Dual-cancer Targeting.  2011년 AAPS 초록.  미국
  • (2011)  Dual drug delivery system for effective controlled combination cancer therapy.  2011 AAPS Annual Meeting and Exposition.  미국
  • (2011)  Local Delivery of Doxorubicin and PEGylated TRAIL loaded PLGA microspheres for Effective and Long-Term Combination Tumor Therapy.  38th Annual Meeting & Exposition of the Controlled Release Society.  미국
  • (2011)  Development and Characterization of PEGylated Recombinant Human Growth Hormone (rhGH) Loaded PLGA Microsphere.  2011 대한약학회 춘계 국제학술대회.  대한민국
  • (2011)  Pharmaceutical Potential of Human Serum Albumin Nanoparticles Surfaced-modified with TNF-related Apoptosis Inducing Ligand (TRAIL) as a Pulmonary Delivery System.  춘계 약학회 초록.  대한민국
  • (2011)  Preparation and Characterization of Inhalable Doxorubicin-loaded Porous Poly (Lactic-co-Glycolic Acid) Microspheres for Treating Lung Cancer.  춘계 약학회 초록.  대한민국
  • (2011)  Sequential Delivery of Dual Drug from PLGA Microspheres for Effective Combination Cancer Therapy.  2011 대한약학회 춘계 국제학술대회.  대한민국
  • (2010)  Improved Biological Half-life and Anti-tumor Activity of Apo2L/TRAIL Using PEG-treated Nanoparticles.  2010 한국약제학회 40주년 국제학술대회.  대한민국
  • (2010)  Non-invasive Delivery System of Lys27-amine Specific PEGylated Exendin-4.  2010 한국약제학회 40주년 국제학술대회.  대한민국
  • (2010)  PEGylated TRAIL loaded Poly(lactic-co-glycolic acid) Micoparticles for Effective Colon Tumor Therapy.  2010 한국약제학회 40주년 국제학술대회.  대한민국
  • (2010)  Preparation and Characterization of PEG-Heparin-based Nanoparticles with Improved Stability for the TRAIL Delivery.  FIP Pharmaceutical Sciences World Congress 2010 in Association with AAPS Annual Meeting and Exposition.  미국
  • (2010)  TNF-related Apoptosis inducing Ligand(TRAIL) Loaded Human Serum Albumin(HSA) Nanoparticle for Enhancing Stablitity and Tumor Distribution.  FIP Pharmaceutical Sciences World Congress 2010 in Association with AAPS Annual Meeting and Exposition.  미국